IFNγ differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract
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چکیده
word count: 141 Manuscript word count: 4,785 Running title: IFNγ and GVHD. This work was supported in part by grants from the Queensland Cancer Fund and NH&MRC. CRE and KPAM are NH&MRC RD Wright Fellows. GRH is an NH&MRC Practitioner Fellow. Corresponding author: Dr Geoffrey Hill, Bone Marrow Transplantation Laboratory, Queensland Institute of Medical Research, 300 Herston Rd, QLD 4006, AUSTRALIA Ph: +61 7 3845 3763, Fax: +61 7 3845 3509 Email: [email protected] Blood First Edition Paper, prepublished online April 20, 2007; DOI 10.1182/blood-2006-12-063982 Copyright © 2007 American Society of Hematology only. For personal use at PENN STATE UNIVERSITY on February 23, 2013. bloodjournal.hematologylibrary.org From
منابع مشابه
IFNgamma differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract.
Although proinflammatory cytokines are key mediators of tissue damage during graft-versus-host disease (GVHD), IFNgamma has previously been attributed with both protective and pathogenic effects. We have resolved this paradox by using wild-type (wt), IFNgamma(-/-), and IFNgammaR(-/-) mice as donors or recipients in well-described models of allogeneic stem cell transplantation (SCT). We show tha...
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تاریخ انتشار 2007